Table 3. Association P-values from Tests With or Without Incorporation of Ancestry Principal Components (PCs) as Covariates in Analyses Involving Non-Caucasians.
Gene | Original | Original—9 participants | Original—9 participants+PCs |
---|---|---|---|
ADORA2A | POMS Anxiety: 0.041 (N=98) | POMS Anxiety: 0.107 (N=89) | POMS Anxiety: 0.114 (N=89) |
SLC6A3 | DEQ Feel: 0.006 (N=84) | DEQ Feel: 0.006 (N=84) | DEQ Feel: 0.013 (N=84) |
ARCI LSD: 0.007 (N=86) | ARCI LSD: 0.007 (N=86) | ARCI LSD: 0.005 (N=86) | |
Diastolic BP: 0.037 (N=95) | Diastolic BP: 0.022 (N=90) | Diastolic BP: 0.068 (N=90) | |
BDNF | POMS Arousal: 0.01 (N=94) | POMS Arousal: 0.013 (N=89) | POMS Arousal: 0.005 (N=89) |
ARCI BG: 0.023 (N=94) | ARCI BG: 0.015 (N=89) | ARCI BG: 0.018 (N=89) | |
Heart rate: 0.023 (N=94) | Heart rate: 0.025 (N=89) | Heart rate: 0.012 (N=89) | |
SLC6A4 | ARCI MBG: 0.046 (N=98) | ARCI MBG: 0.071 (N=90) | ARCI MBG: 0.064 (N=90) |
CSNK1E | DEQ Feel: 0.038 (N=88) | DEQ Feel: 0.064 (N=85) | DEQ Feel: 0.053 (N=85) |
ARCI MBG: 0.008 (N=89) | ARCI MBG: 0.024 (N=87) | ARCI MBG: 0.068 (N=87) | |
SLC6A2 | POMS Pos Mood: 0.012 (N=90) | POMS Pos Mood: 0.012 (N=90) | POMS Pos Mood: 0.008 (N=90) |
POMS Elation: 0.003 (N=90) | POMS Elation: 0.003 (N=90) | POMS Elation: 0.005 (N=90) |
Nine samples from the original analysis were not available for genotyping with the Affymetrix 6.0 microarray and therefore did not have ancestry PCs. Sample size is given in parentheses.