Table 1.
Globaltest results
| KEGG pathway | Analysis | adjP | Statistic | Expected | Std.dev |
|---|---|---|---|---|---|
| Insulin signaling pathway |
OScellvsOB |
1.01∙10-7 |
26.34 |
4.76 |
1.92 |
| |
OScellvsMSC |
3.07∙10-15 |
35.12 |
3.33 |
1.78 |
| Oocyte meiosis |
OScellvsOB |
2.70∙10-7 |
37.45 |
4.76 |
2.9 |
| |
OScellvsMSC |
5.04∙10-16 |
53.7 |
3.33 |
2.84 |
| Ubiquitin mediated proteolysis |
OScellvsOB |
3.21∙10-7 |
22.88 |
4.76 |
1.75 |
| |
OScellvsMSC |
5.04∙10-16 |
37.99 |
3.33 |
1.89 |
| Progesterone-mediated oocyte maturation |
OScellvsOB |
7.16∙10-7 |
34.26 |
4.76 |
2.71 |
| |
OScellvsMSC |
1.34∙10-15 |
55.35 |
3.33 |
2.77 |
| Glycerophospholipid metabolism |
OScellvsOB |
1.40∙10-6 |
27.13 |
4.76 |
2.25 |
| OScellvsMSC | 2.25∙10-15 | 55.86 | 3.33 | 2.82 |
The top five significant pathways with aberrant expression in both osteosarcoma cell lines versus osteoblasts (OScellvsOB) and osteosarcoma cell lines versus mesenchymal stem cells (OScellvsMSC). adjP: FDR-adjusted p-value, Statistic: test statistic of the globaltest, Expected: expected test statistic of the globaltest, Std.dev: standard deviation under the null hypothesis.