Table 3.
Linear regression models predicting Patient’s Assessment of Own Functioning Inventory (PAOFI) memory (n = 188)*
| Base model adjusted R 2 = 0.15 | Base model with BDI-II adjusted R 2 = 0.30 | |||
|---|---|---|---|---|
| Variable | Estimate (95% CI) | P† | Estimate (95% CI) | P † |
| Age | –0.005 (–0.017 to 0.007) | .445 | –0.002 (–0.013 to 0.009) | .739 |
| IQ | 0.00004 (–0.011 to 0.011) | .994 | 0.001 (–0.009 to 0.011) | .833 |
| Treatment | ||||
| Radiation | –0.003 (–0.304 to 0.297) | .983 | 0.017 (–0.257 to 0.290) | .903 |
| Chemotherapy | 0.279 (–0.113 to 0.671) | .162 | 0.090 (–0.272 to 0.452) | .624 |
| Chemotherapy & radiation | 0.466 (0.174 to 0.758) | .002 | 0.374 (0.107 to 0.641) | .006 |
| Verbal memory§ | –0.213 (–0.376 to -0.051) | .010 | –0.174 (–0.322 to –0.025) | .022 |
| BDI-II|| | ----- | ----- | 0.045 (0.030 to 0.059) | <.001 |
* PAOFI memory score transformed with log(x+1). BDI-II = Beck Depression Inventory–II; CI = confidence interval.
† Estimates were tested for H0: estimate = 0 with a t statistic, controlling for all other variables in the regression model; all tests were two-sided.
§ Scores were calculated by comparing participants’ scores against age-corrected normative scores with a mean of 0 and SD of 1, with positive (ie, > 0) scores representing higher/better performance.
|| BDI-II is calculated without the item pertaining to concentration.