Table 1.
Comparison of predicted and experimental steady state vascular endothelial growth factor (VEGF) and soluble VEGF receptor 1 (VEGFR1) levels
Species | Predicted concentration, pM | Range of experimental measurements | References |
---|---|---|---|
Free VEGF | |||
Normal, muscle | 3.2 | 0.3– 3.0 | (7–12) |
Plasma | 2.0 | 0.4– 3.0 | (15) |
Tumor | 26.0 | 8.0– 389.0 | * |
Soluble VEGFR1 | |||
Normal, muscle | 0.3 | 0.5 | (13) |
Plasma | 3.4 | 0.2– 3.0 | (14,16–19) |
Tumor | 23.0 | † | † |
* See Supplementary Table 1 (available online).
† No data available.