Table 3. Correlation of Rac1/Cdc42 expression with wild-type p53 and VEGF protein in 145 breast cancer specimens containing the wild-type p53 protein.
| Variable | No. | Rac1 Expression | p a | Cdc42 Expression | p a | ||
| Positive (%) Negative (%) | Positive (%) Negative (%) | ||||||
| wt-p53 | <.0001b | 30 (44.1) | 38 | .001d | |||
| Positive | 68 | 29 (42.6) | 39 | (55.9) | |||
| Negative | 77 | (57.4) | 54 (70.1) | 23 | |||
| (29.9) | |||||||
| 63 (81.8) | 14 | .007e | |||||
| (18.2) | |||||||
| VEGF | .001c | ||||||
| Positive | 105 | 75 (71.4) | 30 | 68 (64.8) | 37 | ||
| Negative | 40 | (28.6) | (35.2) | ||||
| 17 (42.5) | 23 | 16 (40.0) | 24 | ||||
| (57.5) | (60.0) |
a
The Spearman correlation test was used for statistical analyses. P values <0.05 were considered statistically significant.
b
Correlation coefficient (rs) = −.406.
c
rs = .268.
d
rs = −.263.
e
rs = .224.