Figure 3. Effects of IMD on the LPS-induced changes in body weight, plasma testosterone levels in vivo and H₂O₂-induced change in testosterone production in vitro.

IMD cotreatment restored the decreased body weight (A), plasma testosterone levels (B) 72 h after LPS treatment. IMD also rescued the H₂O₂ suppressed testosterone production from primary Leydig cells (C). All data were expressed as mean ± SEM; * P<0.05 by one-way ANOVA followed by Student–Newmann–Keuls test for (A) and (B); * P<0.05 by Student t-test for (C); n = 5–7.