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. 2013 Jun 4;8(6):e64992. doi: 10.1371/journal.pone.0064992

Figure 4. Peripheral markers of LPS exposure in patients with liver fibrosis correlate with the level of LRAGG.

Figure 4

A) There is a statistically significant increase in the level of LPS Binding Protein (LBP) detected in the sera of patients with mild liver fibrosis (P = 0.0002) and also as a function of liver cirrhosis (P = 0.0013). B) A similar increase is seen in soluble CD14 (sCD14) with the progression of liver fibrosis to liver cirrhosis (P = 0.0020). C) There is a direct correlation between LBP and LRAGG (rS = 0.4168, P<0.0001) and between sCD14 and LRAGG (rS = 0.5287, P<0.0001) (D). rS denotes the Spearman’s correlation coefficient. For panels A & B, samples size is Normal, n = 20; Stage 1–2, n = 21; and Stage 5–6 (Cirrhosis), n = 39.