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. Author manuscript; available in PMC: 2013 Jun 4.
Published in final edited form as: Front Neuroendocrinol. 2009 May 3;30(2):201–211. doi: 10.1016/j.yfrne.2009.04.007

Fig. 4.

Fig. 4

E2 suppresses peripheral cytokines following MCAO. MIP1α /CCL3 was significantly suppressed by E2-treatment after MCAO injury in WT mice (*, P < 0.05), while E2 provided no further suppression in iNOS−/− mice compared to oil-treated controls. As with infarct volume, an effect of genotype was observed in iNOS−/− oil-treated mice which were also protected during stroke compared to WT oil-treated mice (#, P < 0.05, n = 8–12 mice/genotype/treatment). Values represent mean ± SEM.