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. Author manuscript; available in PMC: 2013 Jun 4.
Published in final edited form as: Dev Dyn. 2011 Nov 2;240(12):2673–2679. doi: 10.1002/dvdy.22774

Fig. 2.

Fig. 2

Canonical Wnt signaling induces oral fates during regeneration. Adult polyps were bisected and placed in 1/3× artificial sea water containing either 5 µM alsterpaullone (A–E: oral halves; F: aboral) or DMSO (G–K: oral halves; L: aboral) for 1–9 days. A–E: Polyps undergoing aboral regeneration in the presence of alsterpaullone developed an ectopic oral pole complete with a mouth, pharynx (arrows), and tentacle buds (arrowheads) rather than a physa (G–K). The tentacle buds fail to elongate (compare to L). F: Polyps undergoing oral regeneration in the presence of alsterpaullone formed an oral pole similar to controls (L) but also failed to elongate their tentacles. Aboral regeneration refers to regeneration of lost aboral structures. Scale bar = ≈ 1 mm.