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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Arthritis Rheum. 2013 Jun;65(6):1592–1602. doi: 10.1002/art.37934

Figure 3. ROCK activity in SLE patients versus healthy controls.

Figure 3

(A) PBMCs were obtained from heparinized blood samples of 28 SLE patients and 25 matched healthy controls. Whole cell extracts were prepared and ROCK activation assessed by an ELISA-based ROCK kinase activity assay. Data were analyzed by Mann-Whitney test; **p=0.0015. (B) ROCK activity in the presence or absence of Y-27632 (50 μM) from healthy controls/volunteers and SLE patients. Data were analyzed by Kruskal-Wallis with Dunn’s post test analysis; *p<0.05. Horizontal bars represent medians. Y(50): 50μM Y-27632.