Table 3.
Characteristics of improved versus unimproved patients in the intervention group.
| Characteristic | Somatic depression unimproved N=182 |
Somatic depression Improved N=472 |
p | ||
|---|---|---|---|---|---|
| Demographic characteristics | |||||
| Mean | SD | Mean | SD | ||
| Age (sd) | 59 | 12.1 | 59 | 12.4 | 0.98 |
| N | % | N | % | ||
| Male gender | 115 | 63.2 | 241 | 51.1 | 0.01 |
| Caucasian | 130 | 71.4 | 318 | 67.4 | 0.32 |
| Education≥12 years | 139 | 77.7 | 340 | 73.1 | 0.24 |
| Medical characteristics | |||||
| N | % | N | % | ||
| Hypertension | 112 | 62.2 | 270 | 58.1 | 0.34 |
| High cholesterol | 116 | 69.9 | 268 | 61.3 | 0.05 |
| Diabetes | 56 | 30.9 | 146 | 31.0 | 0.99 |
| Renal insufficiency | 18 | 10.2 | 37 | 8.0 | 0.38 |
| Smoking history | 120 | 66.7 | 302 | 64.7 | 0.63 |
| LVEF <40 | 35 | 23.2 | 95 | 23.9 | 0.87 |
| Killip II-III-IV | 36 | 22.6 | 101 | 23.1 | 0.90 |
| Mean | SD | Mean | SD | ||
| BMI | 29.3 | 5.5 | 28.7 | 5.8 | 0.26 |
| Creatinine (mg/dl) (sd) | 1.2 | 0.8 | 1.1 | 0.7 | 0.23 |
| N | % | N | % | ||
| history of pulmonary disease |
34 | 19.0 | 85 | 18.1 | 0.80 |
| Prior MI | 47 | 26.3 | 103 | 22.3 | 0.29 |
| History of CHF | 24 | 13.8 | 51 | 11.4 | 0.41 |
| prior TIA or stroke | 19 | 10.6 | 28 | 6.0 | 0.05 |
| Prior CABG | 22 | 12.2 | 48 | 10.2 | 0.48 |
| Prior PTCA | 31 | 17.2 | 59 | 12.6 | 0.13 |
| Prior peripheral vascular disease |
28 | 15.9 | 54 | 11.6 | 0.14 |
| Treatment of index MI | |||||
| N | % | N | % | ||
| Thrombolytic therapy | 53 | 29.6 | 173 | 37.0 | 0.08 |
| CABG | 22 | 12.3 | 83 | 18.0 | 0.08 |
| PTCA | 91 | 50.0 | 225 | 48.4 | 0.71 |
| Medications | |||||
| ACE inhibitors | 76 | 42.7 | 190 | 41.9 | 0.86 |
| Vasodilators (non-ACE) | 74 | 42.0 | 181 | 40.6 | 0.74 |
| anticoagulants | 28 | 15.8 | 100 | 22.5 | 0.06 |
| aspirin | 155 | 88.1 | 396 | 86.3 | 0.55 |
| Beta-blockers | 137 | 76.5 | 346 | 76.4 | 0.97 |
| Lipid-lowering drugs | 85 | 48.6 | 194 | 43.0 | 0.21 |
| Antidepressant medication use at baseline |
25 | 13.7 | 41 | 8.7 | 0.06 |
| Antidepressant medication use during follow-up |
74 | 40.7 | 127 | 26.9 | <0.001 |
ACE= angiotensin-converting enzyme; BMI= body mass index; CABG= coronary artery bypass graft; CHF= congestive heart failure; LVEF= left ventricular ejection fraction; MI= myocardial infarction; PTCA= percutaneous transluminal coronary angioplasty; SD= standard deviation; TIA= transient ischemic attack.