Table 1.

Differences in thumb pressure activations in patients and controls across the whole brain.

Side	Region	Coordinates			Z score	Cluster Size
		x	y	z		(KE)
Analysis 1: Pain groups (VVD+FM) > HCs
Ipsilateral	Insula	−36	0	8	3.99*	106
Analysis 2: VVD > HCs
Ipsilateral	Insula	−38	0	4	4.95**	389
Ipsilateral	Posterior cingulated cortex (BA 23)	−4	−26	28	3.86*	67
Contralateral	Anterior cingulated cortex (BA 24)	10	−4	52	3.75*	96
Ipsilateral	Thalamus (VPL) / Globus Pallidus	−20	−12	2	3.66*	22

^**Significant after correction for whole brain multiple comparisons (P_corrected <0.005);

^*Significant after small volume correction (P_corrected < 0.005); VPL – Ventral posterolateral nucleus; BA – Broadmann area.