Table 3.
Group comparisons (≥10 MET h/wk increment in MVPA) and changes in clinical outcomes
| SUS-PA (n=27) | UNSUS-PA (n=68) | LO-PA (n=75) | p-value (group)‡ | p-value (pairwise) ↑ SUS-PA vs. UNSUS-PA, SUS-PA vs. LO-PA, UNSUS-PA vs. LO-PA | |
|---|---|---|---|---|---|
| Primary Outcome | |||||
| FIQ-PI† | 3.1 (0.4) | 2.1 (0.3) | 0.6 (0.3) | <0.01 | 0.15, <0.01, <0.01 |
| Secondary Outcomes | |||||
| FIQ-Total | 21.2 (3.7) | 17.3 (2.3) | 8.6 (2.2) | <0.01 | 0.64, <0.05, <0.05 |
| BPI pain† | 2.0 (0.4) | 1.4 (0.2) | 0.9 (0.2) | <0.05 | 0.36, <0.05, 0.27 |
| PHQ-8† | 4.3 (1.1) | 3.1 (0.7) | 1.7 (0.7) | 0.09 | 0.66, 0.11, 0.28 |
Values represent adjusted mean changes (standard error) from baseline to week 36, with positive values indicating improvement.
P-values were from multiple linear regression analyses and were adjusted for treatment group assignment, response variable value at study entry, baseline level of MVPA, and use of antidepressants.
Pairwise p-values were from Tukey adjusted multiple comparisons, to control for inflated type I error.
Abbreviations: SUS-PA, ≥10 MET h/wk increment in moderate-vigorous physical activity (MVPA)/wk and sustained; UNSUS-PA, ≥10 MET h/wk increment in MVPA, followed by decline; LO-PA, did not achieve ≥10 MET h/wk increment in MVPA; FIQ-PI, Fibromyalgia Impact Questionnaire-Physical Impairment; BPI, Brief Pain Inventory; PHQ-8, Patient Health Questionnaire-8.