Table 4.
Adjusted Odds Ratios (and 95% confidence interval) from logistic regression models for a one standard deviation increase in the natural log of haptoglobin, creatinine corrected haptoglobin, and ACR in relation to outcomes of interest.
| Outcomes of Interest | |||
|---|---|---|---|
| eGFR Decline ≥ 3.3%/year n=51 (25%) |
Persistent Worsening of eGFR n=38 (18.7%) |
Creatinine Increase ≥ 50% n=32 (15.7%) |
|
| Haptoglobin as the Predictor | |||
| Lowest Tertile | 1.00 | 1.00 | 1.00 |
| Second Tertile | 1.67 (0.73, 3.80) | 1.56 (0.62, 3.93) | 1.87 (0.68, 5.09) |
| Third Tertile | 2.13 (0.95, 4.79) | 2.06 (0.83, 5.03) | 2.10 (0.78, 5.68) |
| ROC AUC | 0.577 | 0.584 | 0.611 |
| Haptoglobin/Creatinine as the Predictor | |||
| Lowest Tertile | 1.00 | 1.00 | 1.00 |
| Second Tertile | 2.47 (1.05, 5.79) | 2.46 (0.93, 6.49) | 3.40 (1.15, 10.1) |
| Third Tertile | 2.70 (1.15, 6.32) | 2.72 (1.04, 7.16) | 3.08 (1.02, 9.25) |
| ROC AUC | 0.614 | 0.602 | 0.654 |
| ACR as the Predictor | |||
| Lowest Tertile | 1.00 | 1.00 | 1.00 |
| Second Tertile | 1.13 (0.48, 2.65) | 1.90 (0.72, 5.01) | 1.34 (0.39, 4.64) |
| Third Tertile | 2.50 (1.14, 5.48) | 2.91 (1.16, 7.33) | 5.56 (1.94, 15.9) |
| ROC AUC | 0.621 | 0.620 | 0.709 |
| Haptoglobin/Creatinine and ACR as the Predictors | |||
| ROC AUC | 0.664 | 0.632 | 0.751 |