Table 1.
Characteristic | All (number = 175) |
Favorable (number 111) |
Poor (number = 64) |
P |
---|---|---|---|---|
Age (years old) | 66 ± 11 | 64 ± 11 | 69 ± 10 | 0.002 |
Sex (male, %) | 95 (54.3) | 56 (50.5) | 39 (60.9) | 0.21 |
Initial NIHSS score | 5 (3 to 10) | 4 (2 to 5) | 12 (7 to 16) | < 0.001a |
72 hour-infarct volume (ml)b | 5.9 (1.4 to 35.0) | 3 (1 to 9) | 55 (5 to 215) | < 0.001a |
Sampling time (hours) | 10 (7 to 16) | 10 (7 to 17) | 11 (8 to 15) | 0.66a |
Hypertension (%) | 101 (57.7) | 61 (55.0) | 40 (62.5) | 0.35 |
Diabetes mellitus (%) | 53 (30.3) | 36 (32.4) | 17 (26.6) | 0.50 |
Hyperlipidemia (%) | 42 (24.0) | 26 (23.4) | 16 (25.0) | 0.81 |
Heart failure (%) | 17 (9.7) | 8 (7.2) | 9 (14.1) | 0.19 |
Atrial fibrillation (%) | 53 (30.3) | 21 (18.9) | 32 (50.0) | < 0.001 |
Smoking (%) | 71 (40.6) | 47 (42.3) | 24 (37.5) | 0.63 |
Previous statin use (%) | 26 (14.9) | 17 (15.3) | 9 (14.1) | 0.99 |
Systolic BP (mmHg) | 134 ± 19 | 134 ± 19 | 133 ± 18 | 0.68 |
Diastolic BP (mmHg) | 82 ± 12 | 81 ± 10 | 83 ± 14 | 0.21 |
Creatinine (mg/dl) | 1.07 ± 0.56 | 1.04 ± 0.62 | 1.11 ± 0.42 | 0.46 |
Fasting glucose (mg/dl) | 138 ± 55 | 135 ± 57 | 143 ± 53 | 0.37 |
LDL cholesterol (mg/dl) | 115 ± 37 | 118 ± 29 | 109 ± 47 | 0.17 |
WBC (103/μl) | 7.8 ± 3.0 | 7.7 ± 2.7 | 9.2 ± 3.7 | < 0.01 |
TOAST | < 0.01 | |||
LAA | 52 (29.7) | 35 (31.5) | 17 (26.6) | |
CE | 49 (28.0) | 25 (22.5) | 24 (37.5) | |
SVD | 38 (21.7) | 34 (30.6) | 4 (6.3) | |
Others | 36 (20.6) | 17 (15.3) | 19 (29.7) |
aStatistical analysis conducted using the Mann-Whitney U test; bhyperintense lesion on diffusion-weighted image 72 hours after stroke. BP, blood pressure; CE, cardioembolism; LAA, large-artery atherosclerosis; LDL, low density lipoprotein cholesterol; NIHSS, National Institutes of Health Stroke Scale; SVD, small vessel disease; TOAST, Trial of Org10172 in the Acute Stroke Treatment; WBC, white blood cell.