Table 4.

Receiver operating characteristic (ROC) curve and in-sample reclassification analysis of the addition of each or the combination of IL-6 and hFABP (natural log-transformed) to the baseline clinical model for stroke outcome

	Discrimination		Reclassification
	AUC (95% CI)	Pb	NRI	Pc	IDI	Pd
Baseline clinical modela	0.910 (0.858 to 0.948)	-	-	-
+ logIL-6	0.931 (0.883 to 0.964)	0.075	0.09	0.036	0.03	0.024
+ loghFABP	0.926 (0.877 to 0.960)	0.110	0.07	0.232	0.02	0.032
+ logIL-6 + loghFABP	0.939 (0.893 to 0.970)	0.032	0.18	0.005	0.06	0.001

^aModel with age and initial NIHSS score; ^bP-value for AUC using DeLong method with the baseline clinical model as a reference; ^cP-value for net classification improvement with the baseline clinical model as a reference; ^dP-value for integrated discrimination improvement with the baseline clinical model as a reference. AUC, area under curve; IDI, integrated discrimination improvement; _log, natural log-transformed value; NRI, net reclassification improvement.