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The four ex vivo miniaturized extracorporeal circuits (hemofiltration, hemadsorption with large beads, hemoadsorption with small beads and sham). Blood was circulated through these closed circuits for four hours. HA-LB, hemoadsorption with large beads; HA-SB, hemoadsorption with small beads; HF, hemofiltration; P, mini-pump; RF, replacement fluid; UF, ultrafiltrate.
