Fig. 6.

Chromosomal stability of two C. glabrata clinical isolates with small chromosomes grown in liquid YPD for 70 generations. a Karyotypes of the parental strain Y1644 (lane 1) and eight randomly selected progenies (lanes 2–9), the position of the small chromosome is indicated by a black arrow. Chromosome D rearrangement in one daughter lineage is arrowed in white. b Karyotypes of the parental strain Y1645 (lane 1) and ten (lanes 2–11) randomly selected progenies after 70 generations. The small chromosome is arrowed