Table 2.
Correlation of NGAL and creatinine with various cytokines
NGAL | Crea | |||||||
---|---|---|---|---|---|---|---|---|
6 h sepsis | 24 h sepsis | 6 h sepsis | 24 h sepsis | |||||
r | P-value | r | P-value | r | P-value | r | P-value | |
Crea resp. NGAL | 0.48 | <0.05 | 0.78 | <0.001 | 0.48 | <0.05 | 0.78 | <0.001 |
IL6 | -0.05 | 0.853 | 0.68 | <0.01 | 0.38 | 0.095 | 0.73 | <0.001 |
IL10 | 0.23 | 0.351 | 0.76 | <0.001 | 0.38 | 0.103 | 0.77 | <0.001 |
MCP1 | 0.36 | 0.127 | 0.74 | <0.001 | 0.42 | 0.066 | 0.69 | <0.01 |
IFNγ | 0.25 | 0.293 | 0.22 | 0.383 | 0.37 | 0.114 | 0.03 | 0.909 |
TNFα | 0.60 | <0.01 | 0.70 | <0.01 | 0.39 | 0.09 | 0.69 | <0.01 |
Spearman correlation analyses correlating plasma neutrophil gelatinase-associated lipocalin (NGAL) and creatinine (Crea) with various cytokines, all measured from samples of polymicrobial infected mice 6 h (n = 20) and 24 h (n = 18) post-sepsis induction. P-values are given. IFNγ, interferon-gamma; IL, interleukin; MCP1, monocyte chemotactic protein-1; TNF, tumour necrosis factor