Table 3.
Distribution of baseline qualifying Gram-negative pathogens
| Doripenem | Imipenem | Total | |
|---|---|---|---|
| (N = 79) | (N = 88) | (N = 167) | |
| n (%) | n (%) | n (%) | |
| Specific Gram-negative Pathogens | 65 (82.3) | 62 (70.5) | 127 (76.0) |
| Pseudomonas aeruginosa | 17 (21.5) | 10 (11.4) | 27 (16.2) |
| Monomicrobial* | 8 (10.1) | 6 (6.8) | 14 (8.4) |
| Polymicrobial** | 9 (11.4) | 4 (4.5) | 13 (7.8) |
| Acinetobacter spp. | 15 (19.0) | 10 (11.4) | 25 (15.0) |
| Monomicrobial* | 3 (3.8) | 4 (4.5) | 7 (4.2) |
| Polymicrobial** | 12 (15.2) | 6 (6.8) | 18 (10.8) |
| Enterobacteriaceae | 43 (54.4) | 49 (55.7) | 92 (55.1) |
| Monomicrobial* | 14 (17.7) | 14 (15.9) | 28 (16.8) |
| Citrobacter koseri | 1 (1.3) | 0 | 1 (0.6) |
| Enterobacter aerogenes | 0 | 1 (1.1) | 1 (0.6) |
| Enterobacter cloacae | 4 (5.1) | 3 (3.4) | 7 (4.2) |
| Escherichia coli | 1 (1.3) | 2 (2.3) | 3 (1.8) |
| Klebsiella pneumoniae | 5 (6.3) | 4 (4.5) | 9 (5.4) |
| Pantoea agglomerans | 1 (1.3) | 0 | 1 (0.6) |
| Proteus mirabilis | 1 (1.3) | 2 (2.3) | 3 (1.8) |
| Serratia marcescens | 1 (1.3) | 2 (2.3) | 3 (1.8) |
| Polymicrobial** | 29 (36.7) | 35 (39.8) | 64 (38.3) |
| Citrobacter freundii | 0 | 3 (3.4) | 3 (1.8) |
| Enterobacter aerogenes | 0 | 2 (2.3) | 2 (1.2) |
| Enterobacter asburiae | 1 (1.3) | 0 | 1 (0.6) |
| Enterobacter cloacae | 4 (5.1) | 2 (2.3) | 6 (3.6) |
| Enterobacter spp. (Not Speciated) | 1 (1.3) | 0 | 1 (0.6) |
| Escherichia coli | 5 (6.3) | 12 (13.6) | 17 (10.2) |
| Klebsiella oxytoca | 1 (1.3) | 1 (1.1) | 2 (1.2) |
| Klebsiella pneumoniae | 14 (17.7) | 16 (18.2) | 30 (18.0) |
| Proteus mirabilis | 3 (3.8) | 3 (3.4) | 6 (3.6) |
| Proteus vulgaris | 1 (1.3) | 1 (1.1) | 2 (1.2) |
| Providencia spp. (Not Speciated) | 0 | 1 (1.1) | 1 (0.6) |
| Serratia marcescens | 3 (3.8) | 3 (3.4) | 6 (3.6) |
| Pneumonia with MRS | 7 (8.9) | 4 (4.5) | 11 (6.6) |
| Pseudomonas aeruginosa | 2 (2.5) | 1 (1.1) | 3 (1.8) |
| Polymicrobial** | 2 (2.5) | 1 (1.1) | 3 (1.8) |
| Acinetobacter spp. | 2 (2.5) | 1 (1.1) | 3 (1.8) |
| Polymicrobial** | 2 (2.5) | 1 (1.1) | 3 (1.8) |
| Enterobacteriaceae | 4 (5.1) | 2 (2.3) | 6 (3.6) |
| Polymicrobial** | 4 (5.1) | 2 (2.3) | 6 (3.6) |
*: Monomicrobial pneumonia means a single qualifying pneumonia pathogen was isolated and no other pneumonia pathogen was isolated. **: Polymicrobial pneumonia means at least one qualifying pneumonia pathogen was isolated and at least one other pneumonia pathogen was isolated. MRS, methicillin-resistant Staphylococcus