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. 2012 Nov 15;16(6):R221. doi: 10.1186/cc11866

Table 3.

Antimicrobials most commonly used for empirical treatment of specific infections.

Infection/Drugs Frequency
number (%)a
Infection/Drugs Frequency
number (%)a
Early VAP (<5 days) Suspected catheter-related bacteremia
Piperacillin/tazobactam
Levofloxacin
Ceftriaxone
37/146 (25)
25/146 (17)
19/146 (13)
Vancomycin
Piperacillin/tazobactam
Meropenem
70/171 (41)
21/171 (12)
15/171 (9)

Late VAP (≥5 days) Suspected candidemia and/or invasive
Piperacillin/tazobactam
Meropenem
Ceftazidime
50/142 (35)
23/142 (16)
17/142 (12)
candidiasis
Fluconazole
Caspofungin
Voriconazole
97/151 (64)
32/151 (21)
9/151 (6%)

Community-acquired pneumonia Community-acquired peritonitis
Ceftriaxone
Levofloxacin
Amoxicillin/clavulanic acid
42/156 (27)
31/156 (20)
23/156 (15)
Piperacillin/tazobactam
Ampicillin/sulbactam
Cefotaxime
37/161 (23)
26/161 (16)
16/161 (10)

Hospital-acquired pneumonia Postoperative peritonitis
Piperacillin/tazobactam
Levofloxacin
Ceftriaxone
51/171 (30)
26/171 (15)
22/171 (13)
Piperacillin/tazobactam
Meropenem
Ertapenem
63/165 (38)
46/165 (28)
8/165 (5)

Health-care-acquired pneumonia Purulent meningitis
Piperacillin/tazobactam
Meropenem
Ceftazidime
39/143 (27)
24/143 (17)
13/143 (9)
Ceftriaxone
Linezolid
Cefotaxime
111/156 (71)
6/156 (4)
6/156 (4)

aDenominators represent the number of ICUs that answered the specific question. VAP, ventilator-associated pneumonia.