Table 1.

The baseline variables for all patients and depending on whether a troponin I assay was positive or negative.

Variable	All patients N = 218	Troponin- positive > 0.05, N = 136	Troponin- negative < 0.049, N = 82	P value
Age	36 (16-90)	39 (16-80)	33.5 (16-90)	0.059
Gender (M:F)	103:115 (47%:53%)	67:69	36:46	0.529
Spontaneous survival (Y:N)	106:112	61:75	45:37	0.195
ALF/SALF	178:40	116:20	62:20	0.170
AST	2779 (22-31320)	3154 (38-20000)	2047 (22-31320)	0.0273
Bilirubin	96 (6-1265)	83 (6-739)	122 (9-1265)	0.245
Albumin	30 (16-49)	31 (18-39)	31 (16-49)	0.851
Urea	6.4 (1.5-19.2)	8.8 (2.3-19)	5.2 (1.5-15.9)	0.109
Creatinine	187 (38-929)	192 (38-550)	117 (46-929)	< 0.001
INR	4.4 (1-16)	4.3 (1-15.7)	4.4 (1.2-16)	0.649
pH	7.4 (6.9-7.5)	7.4 (6.9-7.5)	7.4 (7.23-7.5)	0.009
Lactate	2.2 (0.3-24)	2.4 (0.7-24)	2.0 (0.3-11)	0.036
CK	175 (6-37840)	292 (6-37840)	81 (14-1417)	< 0.001
CVVHF	155:63	106:30	49:33	0.006
Inotropes (Y:N)	140:77	99:36	41:41	0.008
NH4	89 (12-346)	88 (12-346)	97 (19-285)	0.545
HE grade	3 (1-4)	4 (1-4)	3 (1-4)	0.017
Heart rate	98 (45-170)	98 (45-160)	99 (50-170)	0.346
MAP	77 (45-180)	70 (50-124)	70 (45-180)	0.308
CVP	13 (4-26)	14 (5-26)	12 (4-22)	0.005
SVO2	80 (55-94)	80 (55-93)	80 (60-94)	0.365
Invasive ventilation	147:71	106:30	41:41	< 0.001
MELD	39 (11-40)	40 (11-40)	37 (12-40)	0.135
APACHE 2	18 (2-51)	19.5 (3-51)	14 (2-51)	0.001
SAPS	46 (12-97)	48 (12-96)	34 (12-97)	0.001
SOFA	14 (2-21)	15 (4-20)	13 (2-21)	0.027

Mann Whitney U test or χ2 test performed as appropriate. ALF, acute liver failure; APACHE, Acute Physiology and Chronic Health Evaluation; AST, aspartate transaminase; CK, creatinine kinase; CVP, central venous pressure; CVVHF, continuous venovenous haemofiltration; HE, hepatic encephalopathy; INR. international normalised ratio; MAP, mean arterial pressure; MELD, model for end stage liver disease; NH4, ammonia; SALF, subacute liver failure; SAPS, Simplified Acute Physiology Score; SOFA, Sequential Organ Failure Assessment; SV02, central venous saturation.