Table 2.
Multivariate analysis of characteristics associated with mortality
| OR (CI 95%) | P value | |
|---|---|---|
| Model 1 | ||
| BDNF 25th quartile | 12.7 (2.2 to 73) | 0.004 |
| Sepsis | 6.3 (1.1 to 39) | 0.04 |
| Age | 1.01 (0.98 to 1.06) | 0.33 |
| Admission SOFA | 1.06 (0.87 to 1.31) | 0.53 |
| Mechanical ventilation | 8.56 (0.92 to 79) | 0.05 |
| Model 2 | ||
| BDNF D2 | 29 (4 to 200) | 0.001 |
| Sepsis | 3.3 (0.56 to 20) | 0.18 |
| Age | 1.04 (0.99 to 1.09) | 0.09 |
| Admission SOFA | 0.91 (0.72 to 1.15) | 0.46 |
| Mechanical ventilation | 14 (1.1 to 175) | 0.038 |
Hosmer and Lemershow goodness-of-fit model 1, χ2 = 2.2; P = 0.97; and model 2, χ2 = 1.9; P = 0.98. BDNF D2, brain-derived neurotrophic factor collected 48 hours after intensive care admission; CI, confidence interval; OR, odds ratio; SOFA, sequential organ-failure assessment.