Table 4.
Brain-derived neurotrophic factor levels in the subset of patients with clinically detectable brain dysfunction
| Survivors (n = 25) | Nonsurvivors (n = 12) | P value | |
|---|---|---|---|
| BDNF D0, mean (SD) | 6,923 (2,994) | 5,580 (3,006) | 0.210 |
| BDNF D2, mean (SD) | 6,748 (2,594) | 3,612 (1,741) | < 0.0001 |
| % variation BDNF, n | |||
| Decrease | 4 | 6 | 0.049 |
| No change/increase | 21 | 6 |
BDNF D0, brain-derived neurotrophic factor collected within 12 hours of enrollment; BDNF D2, brain-derived neurotrophic factor collected 48 hours after intensive care admission.