Table 5.
Differences in parameters likely to trigger renal replacement therapy (RRT) on reaching maximum RIFLE class between patients with and without RRT (matched patients).
| Patients with RRT | Patients without RRT | P value | |
|---|---|---|---|
| Model 1 | N = 383 | N = 726 | |
| Urea (mmol/L) | 15 [10-23] | 15 [11-24] | 0.3 |
| Creatinine (mmol/L) | 217 [158-281] | 214 [158-271] | 0.4 |
| Potassium (mmol/L) | 4.1 [3.6-4.7] | 4.1 [3.6-4.6] | 0.9 |
| pH | 7.34 [7.24-7.44] | 7.36 [7.28-7.44] | 0.5 |
| mSOFA | 7 [5-9] | 5 [3-8] | < 0.001 |
| SAPS II | 50 [38-62] | 43 [34-56] | < 0.01 |
| Urine output (L) | 0.6 [0.2-1.3] | 1.4 [0.7-2.5] | < 0.001 |
| Fluid accumulation (L) | 4 [2-8] | 2 [0-6] | < 0.01 |
| Model 2 | N = 376 | N = 754 | |
| Urea (mmol/L) | 16 [10-23] | 14 [10-22] | 0.9 |
| Creatinine (mmol/L) | 217 [158-286] | 203 [144-265] | 0.12 |
| Potassium (mmol/L) | 4.1 [3.6-4.8] | 4.1 [3.6-4.6] | 0.4 |
| pH | 7.33 [7.24-7.43] | 7.36 [7.27-7.45] | 0.3 |
| mSOFA | 7 [5-10] | 5 [3-8] | < 0.001 |
| SAPS II | 50 [39-63] | 42 [34-54] | < 0.001 |
| Urine output (L) | 0.6 [0.2-1.2] | 1.2 [0.5-2.2] | < 0.001 |
| Fluid accumulation (L) | 4 [2-8] | 2 [1-6] | < 0.03 |
Results are expressed as medians and [interquartile range]. SOFA, Sequential Organ Failure Assessment; mSOFA, SOFA - specific renal component; SAPS, Simplified Acute Physiology Score.