Table 4.
Peak activation foci in the ROI analyses.
| Cluster size | Hemisphere | z-value | x | y | z | |
|---|---|---|---|---|---|---|
| EFFECTS OF CONGRUENCY AND MOTIVATION | ||||||
| INCONGRUENT vs. CONGRUENT | ||||||
| Anterior insula | 57 | R | 7.21* | 33 | 23 | 1 |
| 52 | L | 7.62* | −30 | 26 | −2 | |
| Dorsolateral prefrontal cortex | 66 | R | 5.73* | 42 | 5 | 37 |
| 48 | L | 5.38* | −30 | −7 | 52 | |
| Anterior cingulate cortex | 100 | R | 5.92* | 9 | 14 | 46 |
| 36 | L | 3.75 | −6 | 5 | 46 | |
| Striatum | 63 | R | 6.00* | 12 | 5 | −2 |
| 22 | L | 4.04* | −9 | 8 | 4 | |
| REW vs. NEU | ||||||
| Anterior insula | 58 | R | 6.15* | 33 | 23 | −2 |
| 36 | L | 4.37* | −30 | 29 | −2 | |
| Dorsolateral prefrontal cortex | 103 | R | 4.03 | 36 | 56 | 7 |
| 64 | R | 3.93 | 30 | 5 | 52 | |
| 36 | L | 3.88 | −21 | −4 | 49 | |
| Anterior cingulate cortex | 295 | R | 5.60* | 6 | 32 | 28 |
| 185 | L/R | 4.61* | 0 | 32 | 28 | |
| Striatum | 102 | R | 5.98* | 9 | 17 | −5 |
| 93 | L | 6.64* | −9 | 14 | −5 | |
| PUN vs. NEU | ||||||
| Anterior insula | 55 | R | 5.95* | 33 | 23 | 1 |
| 8 | L | 3.01 | −36 | 20 | 1 | |
| Dorsolateral prefrontal cortex | 48 | L | 4.56* | −33 | −1 | 52 |
| 14 | L | 3.98 | −39 | 8 | 34 | |
| 40 | L | 3.94 | −36 | 41 | 7 | |
| Anterior cingulate cortex | 165 | R | 4.86* | 6 | 26 | 31 |
| Striatum | 89 | R | 4.76* | 12 | 11 | −8 |
| 100 | L | 5.04* | −9 | 11 | −5 | |
| COM vs. NEU | ||||||
| Anterior insula | 56 | R | 6.39* | 33 | 23 | −2 |
| 35 | L | 4.63* | −33 | 20 | −11 | |
| Dorsolateral prefrontal cortex | 96 | R | 5.45* | 30 | 5 | 52 |
| 167 | R | 5.02* | 42 | 53 | 4 | |
| 49 | L | 4.66* | −33 | −1 | 52 | |
| 24 | L | 4.03 | −33 | 41 | 4 | |
| 12 | L | 3.97 | −39 | 8 | 34 | |
| Anterior cingulate cortex | 252 | R | 5.76* | 6 | 32 | 28 |
| 142 | L/R | 4.90* | 0 | 35 | 31 | |
| Striatum | 120 | R | 6.11* | 12 | 17 | −2 |
| 153 | L | 6.36* | −12 | 17 | −5 | |
| REW vs. PUN | ||||||
| Anterior insula | 4 | L | 3.38 | −30 | 26 | −5 |
| Anterior cingulate cortex | 52 | R | 3.75 | 6 | 41 | 16 |
| 51 | L/R | 3.38 | 0 | 35 | 22 | |
| PUN vs. REW | − | − | − | − | − | − |
| COM vs. REW | − | − | − | − | − | − |
| COM vs. PUN | ||||||
| Anterior insula | 7 | L | 3.41 | −33 | 20 | −11 |
| Anterior cingulate cortex | 26 | R | 3.45 | 3 | 35 | 25 |
| 45 | L | 4.12* | −3 | 38 | 25 | |
| CONGRUENCY × MOTIVATION | ||||||
| Dorsolateral prefrontal cortex | 37 | L | 4.05 | −18 | 56 | 16 |
| GENOTYPE-RELATED EFFECTS | ||||||
| A1+ vs. A1− | ||||||
| Anterior insula | 15 | L | 4.08* | −30 | 20 | −8 |
| Dorsolateral prefrontal cortex | 2 | L | 4.04 | −27 | −13 | 49 |
| A1− vs. A1+ | − | − | − | − | − | − |
| CONGRUENCY × MOTIVATION × GENOTYPE | ||||||
| Anterior cingulate cortex | 31 | R | 4.07* | 9 | 38 | 28 |
| 12 | L | 3.44 | −3 | 38 | 31 | |
| Striatum | 4 | R | 3.25 | 21 | −1 | −2 |
Clusters with peak activation p < 0.05, FWE-corrected for ROIs volume with their cluster extent at p < 0.005, uncorrected. Coordinates are given in MNI space (unit mm). R, right; L, left;
*
p-values remained significant after Bonferroni correction for multiple ROIs (N = 8).