Table 3.
Vascular measures of atherosclerosis in juvenile idiopathic arthritis
| Argyropoulou and colleagues [85] | Vlahos and colleagues [87] | Breda and colleagues [86] | |
|---|---|---|---|
| JIA (n) | 31 | 30 | 38 |
| Oligoarticular subtype | 18 | 15 | - |
| Polyarticular subtype | 6 | 8 | - |
| Systemic subtype | 7 | 7 | - |
| Age (years) | 13.6 (3.4 to 26.2) | 12.0 ± 3.0 | 7.1 ± 2.4 |
| Disease duration (years) | 9.1 ± 5.4 | 6.6 ± 3.8 | 22.9 |
| CIMT (mm) | Not reported | 0.46 ± 0.03 (patients) vs. 0.45 ± 0.03 (controls) | 0.38 ± 0.05 (patients)a vs. 0.31 ± 0.05 (controls) |
| FMD (%) | Not reported | 7.10 ± 2.23 (patients)b vs. 9.93 ± 3.90 (controls) | Not reported |
| PWV (m/s) | 3.68 ± 1.59 (patients)a vs. 1.38 ± 0.54 (controls) | 5.5 ± 0.9 (patients) vs. 5.7 ± 1.0 (controls) | Not reported |
| Inflammatory markers | Not reported | Increased | Increased |
| Cytokines/endothelial activation | Not reported | Increased | Increased |
Values are presented as mean ± standard deviation or median (range), unless otherwise specified. CIMT, carotid intima-media thickness; FMD, flow-mediated dilatation; JIA, juvenile idiopathic arthritis; PWV, pulse wave velocity. aDifference from controls is statistically significant (P <0.01). bDifference from controls is statistically significant (P = 0.001).