Table 3.
DACT1 methylation and clinicopathologic features of breast tumors
| Clinicopathologic features | Number (N = 134) | DACT1 methylation status | P value | ||
|---|---|---|---|---|---|
| Methylated | Unmethylated | ||||
| Age (years) | ≤40 | 11 | 2 | 9 | 0.229 |
| > 40 | 86 | 30 | 56 | ||
| Unknown | 37 | 8 | 29 | ||
| Tumor grade | I | 7 | 2 | 5 | 0.425 |
| II | 56 | 21 | 35 | ||
| III | 5 | 1 | 4 | ||
| Unknown | 66 | 16 | 50 | ||
| Tumor size | ≤2.0 cm | 44 | 14 | 30 | 0.21 |
| ≥2.0 cm, ≤5.0 cm | 48 | 18 | 30 | ||
| > 5.0 cm | 4 | 0 | 4 | ||
| unknown | 38 | 8 | 30 | ||
| Lymph node metastasis | Positive | 43 | 16 | 27 | 0.38 |
| Negative | 41 | 12 | 29 | ||
| Unknown | 50 | 12 | 38 | ||
| Distant metastasis | Positive | 1 | 1 | 0 | 0.114 |
| Negative | 98 | 32 | 66 | ||
| Unknown | 35 | 7 | 28 | ||
| ER status | Positive | 45 | 17 | 28 | 0.274 |
| Negative | 29 | 9 | 20 | ||
| Unknown | 60 | 14 | 46 | ||
| PR status | Positive | 34 | 11 | 23 | 0.296 |
| Negative | 40 | 15 | 25 | ||
| Unknown | 60 | 14 | 46 | ||
| HER2 status | Positive | 42 | 15 | 27 | 0.148 |
| Negative | 28 | 11 | 17 | ||
| Unknown | 64 | 14 | 50 | ||
ER, estrogen receptor; HER2, human epidermal growth factor receptor-2; PR, progesterone receptor.