Table 2.
Variable | C-SLE trained (n = 10) |
C-SLE non-trained (n = 9) |
Control (n = 10) |
---|---|---|---|
Time-to-exhaustion, minutes | |||
PRE | 10.1 (2.2)a | 9.7 (1.6)a | 13.7 (2.7)b |
POST | 12.8 (2.4)b | 10.1 (1.8)a | --- |
Resting heart rate, bpm | |||
PRE | 102.6 (10.3)a | 106.1 (12.1)a | 90.5 (15.7)b |
POST | 86.2 (13.8)b | 110.6 (8.4)a | --- |
Peak heart rate, bpm | |||
PRE | 178.2 (18.3)a | 177.6 (17.4)a | 195.8 (8.9)a |
POST | 183.6 (10.5)a | 178.1 (18.6)a | --- |
Peak VO2, ml/Kg/min | |||
PRE | 27.7 (6.1)a | 25.7 (3.1)a | 39.9 (7.3)b |
POST | 31.8 (8.0)b | 25.8 (4.2)a | --- |
Peak speed (Km/h) | |||
PRE | 4.4 (0.6)a | 4.2 (0.5)a | 5.4 (0.9)b |
POST | 5.2 (0.8)b | 4.3 (0.5)a | --- |
Chronotropic reserve, % | |||
PRE | 75.5 (18.7)a | 74.8 (17.3)a | 96.6 (8.2)b |
POST | 87.1 (9.0)b* | 74.1 (18.9)a | --- |
Heart rate, Δ% | |||
Rest to VAT | |||
PRE | 29.8 (16.6)a | 25.3 (12.0)a | 60.0 (24.8)b |
POST | 56.3 (18.7)b | 17.0 (9.5)a | --- |
Rest to RCP | |||
PRE | 53.9 (13.7)a | 54.9 (24.9)a | 97.3 (35.9)b |
POST | 97.4 (28.6)b | 42.8 (17.4)a | --- |
Rest to Peak | |||
PRE | 75.3 (24.8)a | 68.9 (22.9)a | 122.6 (42.1)b |
POST | 117.7 (34.3)b | 61.5 (16.6)a | --- |
Heart rate recovery, ΔHRR | |||
ΔHRR1 | |||
PRE | 25.5 (14.9)a | 26.6 (10.0)a | 40.2 (6.9)b |
POST | 41.5 (10.0)b | 26.3 (8.0)a | --- |
ΔHRR2 | |||
PRE | 36.6 (10.2)a | 35.6 (11.8)a | 57.8 (8.9)b |
POST | 62.2 (13.7)b | 39.8 (9.7)a | --- |
Data are expressed as means (SD) (mixed model for repeated measures). Relative change (Δ%) for heart rate was calculated for the intervals between rest to ventilator anaerobic threshold (VAT), rest to respiratory compensation point (RCP), and rest to peak of exercise. Absolute change (Δ) was used to calculate the difference between heart rate at peak exercise and at the first (ΔHRR1) and second minutes (ΔHRR2) after the exercise test. Means with different letters are significantly different from each other (P < 0.05, between- or within-group comparisons). *P = 0.06, within-group comparison. C-SLE, childhood-onset systemic lupus erythematosus; PRE, pre-intervention (baseline), POST, post-intervention; Peak, peak exercise; VO2, oxygen consumption.