Table 1.
Demographic data and clinical characteristics of patients with adult-onset Still's disease (AOSD), patients with systemic lupus erythematosus (SLE) and healthy controls (HC)
| Characteristics | AOSD (n = 28) |
SLE (n = 28) |
HC (n = 12) |
|---|---|---|---|
| Age at study entry, years | 37.4 ± 14.8 | 38.2 ± 8.7 | 36.4 ± 9.2 |
| Proportion of females | 20 (71.4%) | 25 (89.3%) | 8 (66.7%) |
| Fever (≧39°C) | 28 (100%) | 24 (85.8%) | NA |
| Rash | 25 (89.3%) | 21 (75.0%) | NA |
| Arthritis | 20 (71.4%) | 15 (53.6%) | NA |
| Lymphadenopathy | 7 (25.0%) | 6 (21.4%) | NA |
| Nephritis | 0 (0.0%) | 9 (32.1%)* | NA |
| Ferritin levels, μg/L | 931.0 ± 106.5 | NA | NA |
| AOSD activity score | 5.93 ± 1.46 | NA | NA |
| SLEDAI | N A | 7.8 ± 2.3 | NA |
| C3 levels, mg/dL | NA | 84.6 ± 24.7 | NA |
| C4 levels, mg/dL | NA | 19.5 ± 8.9 | NA |
| Anti-ds DNA, U/mL | NA | 183.2 ± 200.3 | NA |
Data are presented as mean ± SD or number (percentage); NA, not applicable. Nephritis is defined by persistent proteinuria (>0.5 g/24 hours), the presence of cellular casts, or pathological examination of renal biopsy specimens showing lupus nephritis. C3 and C4, complement 3 and 4; Anti-ds DNA, anti-double strand DNA antibody; SLEDAI, SLE disease activity index; *P <0.001, versus AOSD patients.