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. 2013 Feb 14;15(1):R29. doi: 10.1186/ar4165

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Copyright © 2013 Hasegawa et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Cell organization, cell density, and Ki-67 expression in ACL. (A-D) H&E staining; (E-H) Ki-67 (original magnification ×40). Sections of ACL representing (A, E) normal cell distribution in ACL from young normal knee; (B, F) hypocellular ACL from aging knee; (C, G) fibroblast-like cell aggregates in degenerated ACL; (D, H) chondrocyte-like cell aggregates in degenerated ACL. Black arrows, Ki-67-positive cells; white arrows, Ki-67-negative cells. The graph (I) represents the total cell density in each ACL group. The graph (J) represents the percentage of Ki-67-positive cells. The results are presented as mean ± SEM. *P < 0.05; **P < 0.01.