Figure 1. Diffusion MRI fractional anisotropy at baseline correlated strongly with improvements in visuomotor tracking performance during task practice.

To the left, bilateral clusters within the posterior limb of the internal capsule showing a positive correlation of short-term practice scores and FA are illustrated (blue, thickened; FA skeleton in green) (t>3, corrected p<0.05). A scatter plot defining the relationship between FA at the peak voxel within the clusters and short-term practice score is shown on the right. FA explained a majority of the variance in performance scores between patients (r²=0.58). (Note that practice ratios are positive but here we plot the demeaned and orthogonalised values entered into the GLM).