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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: J Immunol. 2013 Jan 4;190(3):1135–1147. doi: 10.4049/jimmunol.1201455

Figure 5.

Figure 5

IFN-γ T cell responses were measured against allele-specific pools both individually and combined for MSP133 3D7/Well (A) and AMA1 3D7/FVO (C). In the right hand graphs, bars shows % change from the strongest single allele peptide pool response, to the response to the combined pool containing allelic peptides; MSP133 3D7/Well (B) and AMA1 3D7/FVO (D). Antagonism is defined as a ≥50% reduction (signified by dotted line) from the IFN-γ gamma response measured to a single peptide compared to when that peptide is combined with its opposing allele. Two volunteers (#10 and #12) are not included in this analysis due to limited d63 PBMC availability, but are included in later analyses. Responses are measured in duplicate, averaged and background subtracted.