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. 2013 Jun 4;104(11):2383–2391. doi: 10.1016/j.bpj.2013.04.030

Table 4.

Identifying the three exponentials from Lanczos

Magnitude Rate (ms−1) τ (ms) Nor. Area Fitted area Area error Fitted τ τ error
1.5576 5 0.2 0.449187 0.449854 0.001485 0.200481 0.002405
0.8607 3 0.3333333 0.413687 0.412555 0.037820 0.332843 0.001471
0.0951 1 1 0.137126 0.137591 0.000937 0.998382 0.001618

Magnitudes and rate constants are from scheme 4-12.17 of Lanczos (7). The time constant (τ) is given by 1/rate. Nor. area is the area of the three exponentials after normalizing to an area of 1.0. The relative error (Eq. 4) for the six estimated parameters was 0.0022 ± 0.0008 (mean ± SD). Estimates are based on 3 × 107 simulated dwell times.