SRCD spectra of MEG-14 in aqueous solution (bold) and in the presence of different detergents and lipids. (a–c) MEG-14 in the presence of micelles: (a) zwitterionic HPS at mole ratios of 1:25 (dot), 1:100 (dash), 1:250 (dot dash), 1:500 (gray); (b) cationic CTAB at 1:25 (dot), 1:50 (dash), 1:250 (dot dash); (c) anionic SDS: 1:25 (dot), 1:100 (dash), 1:250 (dot dash), 1:500 (gray), 1:750 (dashed, gray) protein/detergent molar ratios. (d–f) MEG-14 in the presence of the liposomes: (d) from the PC series: DPPC (dot), DMPC (dash), and with POPC (gray); e) zwitterionic: DSPE (dot), POPE (dash), DPPS (dot dash), and positively charged DOTAP (gray); (f) negatively charged POPG at 1:50 (dot), 1:100 (dash), 1:200 (gray), 1:400 (dot dash), 1:1000 (dash, gray) protein/lipid molar ratios.