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. 2013 Jun 4;104(11):2465–2475. doi: 10.1016/j.bpj.2013.04.027

Figure 2.

Figure 2

Representative force-extension curves and summary unfolding data for human and bovine cMyBP-C. Force-extension curves obtained from (A) recombinant human cMyBP-C and (B) native bovine cMyBP-C obtained at pulling speeds of 3000 and 5000 nm/s, respectively. Stretching individual cMyBP-C molecules resulted in a pattern of sawtooth peaks indicative of Ig/FNIII domain unfolding. Black lines indicate WLC model fits to the data. (C) Plots of unfolding force versus peak position (peak number) for human cMyBP-C (gray circles) and purified native bovine cMyBP-C (black squares).