Figure 3.

Force-extension curves showing anomalous force drops. (A) Three force versus extension curves obtained from human cMyBP-C in three independent experiments are shown superimposed. Each curve shows a distinct force drop at the 6th unfolding peak (gray arrow). (B) A full-length force-extension curve of a human cMyBP-C molecule. Gray arrow indicates a force drop at the 5th unfolding peak. (C) Example force versus extension curves for human (a and b) and bovine (c and d) cMyBP-C. Gray arrows indicate force drops at various locations.