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Kinetic parameters obtained from Monte Carlo simulations
| Kinetic parameters | Human cMyBP-C | Bovine cMyBP-C | Mouse cMyBP-C | |
|---|---|---|---|---|
| Monte Carlo simulation | ΔG (kcal/mol) | 15.53 | 16.4 | 14.7 |
| Δx (nm) | 0.42 | 0.53 | 0.315 |
ΔG is the calculated free energy barrier between the folded and unfolded state at zero force, Δx is the distance between the folded state and the transition state along the unfolding reaction coordinate (i.e., width of the unfolding potential).
