Table 3.
Variance components, ICCs, attenuation bias in logistic regression coefficients, and associated potential attenuation of odds ratios in a hypothetical epidemiologic study.
| Chemical class/ pesticide | σ2BW (95% CI) | σ2WI (95% CI) | ICCa | Percent attenuation biasb | ORobs if ORtrue = 2.0c |
|---|---|---|---|---|---|
| Carbamates | |||||
| Carbaryl | 1.1 (–0.04, 2.3) | 1.3 (0.73, 2.0) | 0.45 | –55 | 1.4 |
| Propoxur | 2.0 (0.41, 3.6) | 0.75 (0.33, 1.2) | 0.73 | –27 | 1.7 |
| Organochlorines | |||||
| Chlordane | 3.2 (1.2, 5.1) | 0.16 (0.10, 0.23) | 0.95 | –5 | 1.9 |
| Methoxychlor | 1.8 (–0.31, 3.8) | 1.5 (0.36, 2.7) | 0.54 | –46 | 1.5 |
| Organophosphates | |||||
| Chlorpyrifos | 0.40 (0.01, 0.79) | 0.43 (0.25, 0.61) | 0.48 | –52 | 1.4 |
| Diazinon | 3.0 (0.47, 5.5) | 0.99 (0.46, 1.5) | 0.75 | –25 | 1.7 |
| Pyrethroids | |||||
| Cyfluthrin | 1.6 (0.28, 2.8) | 0.84 (0.48, 1.2) | 0.65 | –35 | 1.6 |
| Cypermethrin | 3.6 (0.97, 6.2) | 0.74 (0.42, 1.1) | 0.83 | –17 | 1.8 |
| Permethrin | 2.4 (0.78, 4.0) | 0.37 (0.22, 0.53) | 0.87 | –13 | 1.8 |
| Synergist | |||||
| Piperonyl butoxide | 6.2 (1.5, 11) | 0.99 (0.56, 1.4) | 0.86 | –14 | 1.8 |
| Herbicides | |||||
| Dacthal | 2.2 (0.42, 3.9) | 0.96 (0.35, 1.6) | 0.69 | –31 | 1.6 |
| Simazine | 1.3 (–0.36, 2.9) | 2.2 (1.2, 3.1) | 0.37 | –63 | 1.3 |
| Trifluralin | 1.5 (0.44, 2.7) | 0.32 (0.10, 0.54) | 0.83 | –17 | 1.8 |
| Abbreviations: Abbreviations: σ2BW, between-home variance; σ2W, within-home variance; CI, confidence interval; ICC, intraclass correlation coefficient. aσ2BW/(σ2BW + σ2WI). b[(β1,obs – β1,true)/β1,true] × 100%. cORtrueICC. | |||||