Figure 7.

Nonhematopoietic Cav1 loss rather than higher regulatory T-cell numbers protects against atherosclerosis in Cav1^−/−Apoe^−/− mice. Quantitative analysis of the percentages of CD3⁺ T cells (A), CD8⁺ cytotoxic T cells (B), CD4⁺ helper T cells (C), and CD4⁺ CD25⁺ FoxP3⁺ regulatory T cells (D) of the bone marrow- transplanted Cav1^+/+Apoe^−/− and Cav1^−/−Apoe^−/− mice. Lymph node samples were analyzed using flow cytometry (n=5–8 animals/group). Cav1^+/+→, transplanted with Cav1^+/+Apoe^−/− bone marrow; Cav1^−/−→, transplanted with Cav1^−/−Apoe^−/− bone marrow. Values are means ± se. *P < 0.05.