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. 2013 Mar 19;121(6):663–669. doi: 10.1289/ehp.1205823

Figure 1.

Figure 1

Effect of BPA on E2 serum concentration (A) and duration of the estrus phase (B). Adult female rats were administered BPA (0, 0.001, or 0.1 mg/kg BWU/day) or EB (0.001 mg/kg BW/day) for 90 days by gavage. E2 levels were measured by ELISA (A), and staging of the estrous cycle was determined by a vaginal smear (B). Values represent the mean ± SD (n = 12). *p < 0.05, **p < 0.01, and ***p < 0.001, compared with control (0 mg/kg BW).

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