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. Author manuscript; available in PMC: 2013 Jun 5.
Published in final edited form as: Nat Rev Cancer. 2010 Jan;10(1):51–57. doi: 10.1038/nrc2772

Table 2. Human tumours showing cell senescence.

Associated oncogenic
event
Tissue/Tumour Evidence of senescence Refs.
NF1 inactivation Dermal neurofibromas SABG, INK4A 26
BRAFV600E Nevi SABG, INK4A, low Ki67 29
not determined Prostate PIN SABG, CXCR2 6, 52
not determined Colon adenomas SABG, INK4A, IL8 27, 28,
53