Skip to main content
. Author manuscript; available in PMC: 2013 Jun 5.
Published in final edited form as: J Antimicrob Chemother. 2008 May 7;62(1):161–167. doi: 10.1093/jac/dkn187

Figure 2.

Figure 2

Saquinavir percentile curves (P10, P25 and P50) from 12 to 24 h post-dose (shown for 1600/100 mg once daily only). The graph represents the exponential decline described by C = C0×e−kt used to calculate t < MEC, i.e. the length of time patients were below the MEC (<100 ng/mL) before the next dosing interval. C0 represents the time at 12 h post-dose, C the saquinavir MEC of 100 ng/mL and tMEC (or t) the time when concentrations reached 100 ng/mL (data shown for P25 only).