Table 1.
Intensities and Ratios of N-glycans derived from cancer, Barrett’s, HGD and DF HBS samples that have demonstrated significant changes in abundances (0.8>H/L>1.2).
| Structures | Disease free(L) | Cancer (H) | Ratio (H/L) | Disease free(L) | Barrett’s (H) | Ratio (H/L) | Disease free(L) | HGD (H) | Ratio (H/L) |
|---|---|---|---|---|---|---|---|---|---|
|
4.57E+08 | 6.94E+08 | 1.52 | 1.25E+09 | 5.18E+09 | 4.14 | 1.33E+09 | 4.33E+09 | 3.25 |
|
------- | ------- | ------- | 1.01E+08 | 6.91E+07 | 0.68 | 1.26E+08 | 6.63E+07 | 0.53 |
|
4.78E+08 | 3.78E+08 | 0.79 | 5.25E+08 | 2.84E+08 | 0.54 | 5.61E+08 | 7.99E+08 | 1.42 |
|
------- | ------- | ------- | 3.56E+08 | 2.28E+09 | 0.64 | 3.63E+08 | 1.91E+09 | 5.26 |
|
1.81E+08 | 4.79E+07 | 0.26 | ------- | ------- | ------- | 4.93E+08 | 6.30E+08 | 1.28 |
|
------- | ------- | ------- | 1.14E+10 | 1.49E+10 | 1.30 | 2.20E+10 | 3.13E+10 | 1.42 |
|
------- | ------- | ------- | 6.32E+08 | 7.91E+08 | 1.25 | 9.38E+08 | 1.15E+09 | 1.23 |
|
1.18E+08 | 1.57E+08 | 1.33 | 6.77E+07 | 1.05E+09 | 15.5 | 7.72E+07 | 1.46E+09 | 18.9 |
|
------- | ------- | ------- | 2.75E+08 | 8.35E+08 | 3.03 | 2.22E+08 | 8.23E+08 | 3.70 |
|
9.79E+08 | 1.88E+08 | 0.19 | 6.22E+08 | 4.68E+08 | 0.75 | 8.23E+08 | 5.56E+08 | 0.68 |
|
1.72E+08 | 2.89E+07 | 1.68 | 2.12E+08 | 2.82E+08 | 1.33 | ------- | ------- | ------- |
|
4.92E+08 | 3.43E+08 | 0.69 | 4.21E+08 | 8.95E+08 | 2.12 | 4.35E+08 | 8.81E+08 | 2.02 |
|
------- | ------- | ------- | 5.75E+09 | 3.64E+09 | 0.63 | 5.92E+09 | 4.14E+09 | 0.69 |
|
------- | ------- | ------- | 3.42E+08 | 1.51E+09 | 4.44 | 3.23E+08 | 1.43E+09 | 4.43 |
|
7.14E+08 | 3.71E+08 | 0.52 | 5.95E+08 | 1.44E+09 | 2.42 | 5.32E+08 | 9.81E+08 | 1.84 |
|
4.26E+09 | 6.80E+08 | 1.60 | 4.14E+09 | 1.50E+09 | 0.36 | 4.12E+09 | 5.87E+09 | 1.42 |
|
5.35E+08 | 2.22E+09 | 0.41 | 3.58E+08 | 3.36E+09 | 9.39 | 3.35E+08 | 3.39E+09 | 0.10 |
|
9.44E+09 | 7.13E+09 | 0.76 | 6.77E+09 | 9.88E+09 | 1.46 | 7.04E+09 | 7.43E+09 | 1.06 |
|
|
8.99E+09 | 6.25E+09 | 0.70 | ------- | ------- | ------- | 7.87E+09 | 5.44E+09 | 0.69 |
|
1.77E+08 | 5.38E+07 | 0.30 | 1.31E+08 | 6.60E+08 | 5.03 | 1.55E+08 | 5.16E+08 | 3.32 |
|
1.31E+10 | 7.39E+09 | 0.56 | 1.21E+10 | 1.53E+10 | 1.26 | ------- | ------- | ------- |
|
1.81E+10 | 1.43E+10 | 0.79 | 1.35E+10 | 3.39E+10 | 2.51 | 1.40E+10 | 2.95E+10 | 2.10 |
|
4.82E+09 | 3.44E+09 | 0.71 | 3.17E+09 | 8.20E+09 | 2.59 | 3.21E+09 | 8.01E+09 | 2.50 |
|
------- | ------- | ------- | ------- | ------- | ------- | 5.92E+07 | 4.28E+08 | 7.23 |
|
2.07E+09 | 1.24E+09 | 0.60 | 1.89E+09 | 3.48E+09 | 1.84 | 1.89E+09 | 2.34E+09 | 1.23 |
|
|
1.52E+10 | 8.88E+09 | 0.58 | ------- | ------- | ------- | 1.29E+09 | 4.96E+09 | 3.84 |
|
|
------- | ------- | ------- | 1.26E+09 | 3.48E+09 | 2.76 | 1.24E+09 | 3.67E+09 | 2.96 |
|
9.38E+08 | 3.64E+08 | 0.39 | 7.84E+08 | 4.69E+09 | 0.60 | 7.93E+08 | 3.18E+09 | 4.01 |
|
------- | ------- | ------- | ------- | ------- | ------- | 9.79E+07 | 4.07E+08 | 4.16 |
|
------- | ------- | ------- | 1.28E+11 | 1.62E+11 | 1.27 | 1.40E+11 | 1.98E+11 | 1.41 |
|
3.15E+10 | 2.12E+10 | 0.67 | ------- | ------- | ------- | 2.99E+10 | 3.69E+10 | 1.23 |
|
|
1.27E+10 | 5.23E+09 | 0.41 | 1.20E+10 | 2.06E+10 | 1.72 | 1.30E+10 | 1.53E+10 | 1.18 |
|
4.77E+09 | 1.29E+09 | 0.27 | 4.52E+09 | 1.95E+09 | 0.43 | 5.21E+09 | 2.51E+09 | 0.48 |
|
------- | ------- | ------- | 1.03E+09 | 2.30E+09 | 2.23 | 8.33E+08 | 2.32E+09 | 2.79 |
|
4.72E+10 | 2.48E+10 | 0.53 | 3.51E+10 | 4.30E+10 | 1.23 | ------- | ------- | ------- |
|
9.09E+08 | 4.60E+08 | 0.51 | 7.07E+08 | 9.78E+08 | 1.38 | 8.27E+08 | 1.15E+09 | 1.39 |
|
1.12E+09 | 1.56E+08 | 0.14 | 8.72E+08 | 3.97E+08 | 0.46 | ------- | ------- | ------- |
|
|
2.97E+10 | 2.36E+10 | 0.79 | 2.39E+10 | 4.13E+10 | 1.73 | 3.04E+10 | 3.93E+10 | 1.29 |
|
------- | ------- | ------- | 8.10E+09 | 1.17E+10 | 1.44 | 1.01E+10 | 1.32E+10 | 1.31 |
|
5.86E+09 | 4.30E+09 | 0.73 | 4.26E+10 | 4.65E+09 | 0.10 | ------- | ------- | ------- |
|
1.81E+09 | 8.55E+07 | 0.05 | 1.34E+09 | 6.48E+08 | 0.48 | 1.67E+09 | 4.24E+08 | 0.25 |
|
6.32E+10 | 1.84E+10 | 0.29 | 3.39E+10 | 4.58E+10 | 1.35 | ------- | ------- | ------- |
|
2.12E+09 | 1.05E+08 | 0.05 | 1.78E+09 | 5.27E+08 | 0.30 | 1.65E+09 | 1.68E+09 | 1.01 |
|
------- | ------- | ------- | ------- | ------- | ------- | 4.51E+08 | 2.77E+08 | 0.61 |
|
------- | ------- | ------- | 3.39E+10 | 4.58E+10 | 1.35 | 2.31E+10 | 5.64E+10 | 2.44 |
|
3.03E+09 | 3.88E+09 | 1.28 | 2.33E+09 | 7.19E+09 | 3.09 | 2.68E+09 | 8.08E+09 | 3.01 |
|
------- | ------- | ------- | 1.73E+09 | 8.17E+08 | 0.47 | 4.47E+08 | 9.41E+08 | 2.10 |
|
------- | ------- | ------- | 1.39E+09 | 4.00E+09 | 2.88 | 1.71E+09 | 4.34E+09 | 2.53 |
|
5.64E+09 | 2.91E+09 | 0.51 | 4.53E+09 | 2.92E+09 | 0.64 | 5.58E+09 | 7.23E+09 | 1.29 |
|
2.20E+10 | 2.30E+09 | 0.10 | ------- | ------- | ------- | 1.16E+10 | 5.93E+09 | 0.51 |
|
2.02E+09 | 1.54E+09 | 0.76 | 1.05E+09 | 2.32E+09 | 2.20 | 2.73E+08 | 5.80E+09 | 21.2 |
|
1.07E+10 | 6.47E+09 | 0.60 | ------- | ------- | ------- | 6.44E+09 | 2.31E+10 | 3.58 |
|
8.55E+08 | 6.89E+07 | 0.81 | ------- | ------- | ------- | ------- | ------- | ------- |
|
5.40E+09 | 7.17E+09 | 1.32 | 4.56E+09 | 2.18E+10 | 4.78 | 5.13E+09 | 2.14E+10 | 4.17 |
|
------- | ------- | ------- | ------- | ------- | ------- | 4.62E+08 | 1.87E+08 | 0.40 |
|
9.33E+08 | 2.96E+09 | 3.17 | 1.30E+09 | 4.16E+09 | 3.20 | 9.26E+08 | 3.09E+09 | 3.34 |
|
1.10E+08 | 5.71E+08 | 5.42 | 1.66E+08 | 3.07E+09 | 18.49 | 1.94E+08 | 1.79E+09 | 9.22 |
|
4.95E+07 | 1.14E+07 | 0.23 | 5.37E+07 | 7.90E+08 | 14.70 | 9.02E+07 | 8.44E+08 | 9.35 |
Symbols:Fucose
; N-acetyl glucosamine
; mannose
; galactose
; sialic acid

Glycans structures designated with asterisks were identified through tandemMS and mass accuracy (<1).
Glycan structures without asterisks were only identified through mass accuracy (<1)