Table 3.
Regression analysis comparing placental morphometry indices with sonographic and maternal serum markers. Data presented as coefficients and 95% confidence intervals (CI).
| Uterine artery PI (95% CI) | *4D placental volume (95% CI) | * VI (95% CI) | * FI (95% CI) | * VFI (95% CI) | hCG (95% CI) | PAPP-A (95% CI) | ADAM12s (95% CI) | PP13 (95% CI) | |
|---|---|---|---|---|---|---|---|---|---|
| Placental volume at morphometry (cm3) | −69.1 (−150–12.0) | 0.56 (−1.85–2.98) | −1.00 (−6.06–4.06) | −0.38 (−5.25–4.50) | −3.29 (−12.9–6.41) | 26.4 (−51.4–104) | 41.9 (−21.1–105.3) | 4.4 (−98.4–107.30) | 78.0 (−0.9–156.9) |
| P = 0.09 | P = 0.64 | P = 0.69 | P = 0.88 | P = 0.50 | P = 0.50 | P = 0.19 | P = 0.93 | P = 0.05 | |
| Terminal villi volume (cm3) | −11.7 (−50.5–27.1) | −0.13 (−1.25–1.0) | −1.09 (−3.4–1.2) | −1.0 (−3.2–1.2) | −3.1 (−7.5–1.3) | 13.1 (25.4–51.5) | 30.2 (−0.21–60.7) | −5.8 (−53.4–41.7) | 4.8 (−33.5–43.1) |
| P = 0.55 | P = 0.81 | P = 0.35 | P = 0.37 | P = 0.16 | P = 0.50 | P = 0.05 | P = 0.81 | P = 0.80 | |
| Terminal villi surface area (m2) | −0.04 (−2.2–2.1) | −0.03 (−0.09–0.04) | −0.09 (−0.2–0.04) | −0.02 (−0.1–0.10) | −0.2 (−0.4–0.05) | 0.10 (−2.0–2.2) | 1.06 (−0.6–2.73) | −1.14 (−3.8–1.52) | −0.15 (−2.3–1.99) |
| P = 0.97 | P = 0.38 | P = 0.16 | P = 0.74 | P = 0.11 | P = 0.92 | P = 0.21 | P = 0.39 | P = 0.88 | |
| Terminal villi length (km) | 1.49 (−10.4–13.4 | 0.02 (−0.36–0.32) | −0.24 (−0.96–0.47) | 0.14 (−0.55–0.83) | −0.42 (−1.80–0.96) | −0.93 (−12.4–10.5) | 0.82 (−8.6–10.3) | −1.92 (−16.8–12.9) | 6.54 (−5.3–18.4) |
| P = 0.80 | P = 0.88 | P = 0.50 | P = 0.68 | P = 0.55 | P = 0.87 | P = 0.86 | P = 0.80 | P = 0.27 |
*
4D placental volume and indices are adjusted for current maternal BMI and posterior location of placenta.
PI = pulsatility index, VI = vascularization index, FI = flow index, VFI = vascularization flow index.