GABAA receptor activation attenuates bAP-induced calcium transients. (A) Alexa 594 and OG-1 filled layer 2/3 PN with white box marking ROI. (B) Dendritic calcium transients and corresponding somatic APs showing reversible effect of the GABAA receptor agonist isoguvacine HCl (IGHC, 30 μM). Scale bars: calcium: 250 ms, 10% ΔF/F0; AP: 20 ms, 20 mV. (C) Group time course for calcium transients and somatic APs (n= 6). (D) Scatter plot showing peak calcium amplitudes from individual cells before, during, and after IGHC application. *P < 0.05.