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. 2013 Feb 22;121(5):551–557. doi: 10.1289/ehp.1205880

Figure 2.

Figure 2

Airway responsiveness of mice 24 hr after exposure. Mice were unexposed, exposed to O3, or treated with anti–IL-13 24 hr before O3 exposure. Methacholine-induced changes in G, a measure of the lung tissue response in WT (A), TNFR2–/– (B), Cpefat (C), and Cpefat/TNFR2–/– (D) mice. Values shown are mean + SE of data from 6–9 mice per group. *p < 0.05, O3-exposed compared with unexposed genotype-matched mice. **p < 0.05, compared with TNFR2 genotype-matched mice with the same exposure. #p < 0.05, compared with obesity-matched TNFR2-sufficient mice with the same O3 exposure. ##p < 0.05, compared with O3-exposed genotype-matched mice not treated with anti–IL-13.