Table 1.

Effect of IL-13 blockade or TNFR2 deficiency on O₃-induced increases in airway responsiveness, BAL neutrophil numbers, and pulmonary mechanics in lean and obese mice.

Intervention	Lean mice			Obese mice
	Airway responsiveness	BAL neutrophils	Pulmonary mechanics	Airway responsiveness	BAL neutrophils	Pulmonary mechanics
IL-13 blockade	No change	No change	No change	No change	Decrease	Decrease
TNFR2 deficiency	Decrease	No change	No change	Increase	Decrease	Decrease
Outcomes (no change, increase, decrease) indicate the qualitative change in the response to O3 relative to the absence of IL-13 blockade or TNFR2 deficiency.