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. 2013 Feb 20;121(5):613–618. doi: 10.1289/ehp.1206066

Figure 5.

Figure 5

Effect of TCDD (10–10 to 10–8 M) on AChE enzymatic activity (A) and promoter activity (B) in PC12 rat neuronal cells. (A) AChE enzymatic activity in cells incubated with TCDD or 0.1% DMSO (control) for 24 hr. (B) The mouse ACHE promoter–reporter construct (pAChEm-Luc) was transiently transfected into PC12 cells 1 day before treatment; after 24 hr of treatment with TCDD or DMSO, promoter activity was determined by luciferase assays. Values were calculated as a percentage of control and are expressed as mean ± SE (n = 3); each independent sample was tested in triplicate.