Table 3.
Electrophysiological characteristics of GPi neurons with subjects at rest versus during voluntary movement
| HD | PD | |||||
|---|---|---|---|---|---|---|
| rest | movement | p-value | rest | movement | p-value | |
| # of neurons† | 8 | 8 | 23 | 23 | ||
| Mean firing rate | 57.92 +/− 18.24 | 67.12 +/− 21.22 | 0.012* | 85.50 +/− 18.65 | 102.06 +/− 24.12 | 0.007* |
| Burst index | 4.89 +/− 1.79 | 3.97 +/− 1.18 | 0.050* | 2.44 +/− 0.83 | 2.26 +/− 0.69 | NS |
| Proportion of spikes in bursts | 0.071 +/− 0.065 | 0.048 +/− 0.40 | 0.050* | 0.066 +/− 0.069 | 0.033 +/− −.53 | 0.010* |
| L-statistic | 5.50 +/− 0.53 | 5.38 +/− 0.52 | NS | 5.00 +/− 0.80 | 4.57 +/− 0.79 | 0.026* |
denotes statistically significant difference between rest and voluntary movement by Wilcoxin paired sample test
Only neurons studied both at rest and during voluntary movement are included in this comparison